| Syston to Spello | 922.64 mi (1,484.85 km) |
| Syston to Spilamberto | 787.75 mi (1,267.75 km) |
| Syston to Spilimbergo | 772.61 mi (1,243.39 km) |
| Syston to Spinea | 776.85 mi (1,250.23 km) |
| Syston to Spoleto | 935.66 mi (1,505.80 km) |
| Syston to Spoltore | 998.26 mi (1,606.55 km) |
| Syston to Spresiano | 766.03 mi (1,232.81 km) |
| Syston to Squinzano | 1,235.44 mi (1,988.25 km) |
| Syston to Statte | 1,199.71 mi (1,930.74 km) |
| Syston to Stezzano | 685.83 mi (1,103.74 km) |
| Syston to Strada | 848.22 mi (1,365.08 km) |
| Syston to Stradella | 705.22 mi (1,134.95 km) |
| Syston to Striano | 1,101.00 mi (1,771.88 km) |
| Syston to Subiaco | 993.72 mi (1,599.23 km) |
| Syston to Sulmona | 1,013.26 mi (1,630.69 km) |
