| Syston to Santa Venerina | 1,297.39 mi (2,087.94 km) |
| Syston to Santeramo in Colle | 1,172.82 mi (1,887.48 km) |
| Syston to Santo Stefano di Magra | 774.17 mi (1,245.91 km) |
| Syston to Santo Stino di Livenza | 783.64 mi (1,261.14 km) |
| Syston to Sarezzo | 703.39 mi (1,131.99 km) |
| Syston to Sarno | 1,102.55 mi (1,774.39 km) |
| Syston to Saronno | 668.00 mi (1,075.04 km) |
| Syston to Sarzana | 778.21 mi (1,252.41 km) |
| Syston to Sassari | 943.03 mi (1,517.67 km) |
| Syston to Sasso Marconi | 802.19 mi (1,291.01 km) |
| Syston to Sassuolo | 779.49 mi (1,254.47 km) |
| Syston to Sava | 1,220.85 mi (1,964.77 km) |
| Syston to Saviano | 1,093.89 mi (1,760.45 km) |
| Syston to Savigliano | 682.61 mi (1,098.55 km) |
| Syston to Savignano sul Panaro | 790.92 mi (1,272.86 km) |
