| Syracuse to Sestu | 4,239.74 mi (6,823.21 km) |
| Syracuse to Settimo Torinese | 3,967.55 mi (6,385.16 km) |
| Syracuse to Seveso | 4,006.86 mi (6,448.42 km) |
| Syracuse to Sezze | 4,327.05 mi (6,963.72 km) |
| Syracuse to Siano | 4,424.04 mi (7,119.81 km) |
| Syracuse to Siena | 4,183.58 mi (6,732.83 km) |
| Syracuse to Signa | 4,156.42 mi (6,689.11 km) |
| Syracuse to Silea | 4,136.45 mi (6,656.97 km) |
| Syracuse to Silvi Paese | 4,330.17 mi (6,968.73 km) |
| Syracuse to Sinalunga | 4,204.35 mi (6,766.25 km) |
| Syracuse to Siniscola | 4,217.43 mi (6,787.31 km) |
| Syracuse to Sinnai | 4,244.56 mi (6,830.95 km) |
| Syracuse to Siracusa | 4,602.93 mi (7,407.71 km) |
| Syracuse to Solaro | 4,005.64 mi (6,446.46 km) |
| Syracuse to Soliera | 4,113.73 mi (6,620.41 km) |
