| Syracuse to Santa Venerina | 4,570.58 mi (7,355.64 km) |
| Syracuse to Santeramo in Colle | 4,511.74 mi (7,260.94 km) |
| Syracuse to Santo Stefano di Magra | 4,092.62 mi (6,586.44 km) |
| Syracuse to Santo Stino di Livenza | 4,149.28 mi (6,677.63 km) |
| Syracuse to Sarezzo | 4,050.59 mi (6,518.80 km) |
| Syracuse to Sarno | 4,420.17 mi (7,113.57 km) |
| Syracuse to Saronno | 4,003.32 mi (6,442.73 km) |
| Syracuse to Sarzana | 4,096.30 mi (6,592.36 km) |
| Syracuse to Sassari | 4,161.84 mi (6,697.83 km) |
| Syracuse to Sasso Marconi | 4,139.75 mi (6,662.29 km) |
| Syracuse to Sassuolo | 4,114.80 mi (6,622.13 km) |
| Syracuse to Sava | 4,561.89 mi (7,341.65 km) |
| Syracuse to Saviano | 4,411.90 mi (7,100.26 km) |
| Syracuse to Savigliano | 3,978.88 mi (6,403.39 km) |
| Syracuse to Savignano sul Panaro | 4,127.64 mi (6,642.80 km) |
