| Syosset to Santa Paula (California) | 2,505.72 mi (4,032.57 km) |
| Syosset to Santa Rosa (California) | 2,588.89 mi (4,166.41 km) |
| Syosset to Santaquin (Utah) | 1,999.69 mi (3,218.20 km) |
| Syosset to Santee (California) | 2,440.63 mi (3,927.82 km) |
| Syosset to Sapulpa (Oklahoma) | 1,263.73 mi (2,033.78 km) |
| Syosset to Saraland (Alabama) | 1,066.52 mi (1,716.39 km) |
| Syosset to Sarasota (Florida) | 1,063.81 mi (1,712.03 km) |
| Syosset to Sarasota Springs (Florida) | 1,063.78 mi (1,711.99 km) |
| Syosset to Saratoga (California) | 2,582.26 mi (4,155.74 km) |
| Syosset to Saratoga Springs (New York) | 156.22 mi (251.41 km) |
| Syosset to Saratoga Springs (Utah) | 1,999.67 mi (3,218.16 km) |
| Syosset to Sartell (Minnesota) | 1,091.13 mi (1,756.00 km) |
| Syosset to Satellite Beach (Florida) | 961.35 mi (1,547.15 km) |
| Syosset to Sauk Rapids (Minnesota) | 1,087.69 mi (1,750.48 km) |
| Syosset to Sault Ste. Marie (Michigan) | 668.79 mi (1,076.32 km) |
