| Syosset to Enterprise (Nevada) | 2,261.70 mi (3,639.85 km) |
| Syosset to Enumclaw (Washington) | 2,409.65 mi (3,877.95 km) |
| Syosset to Ephrata (Pennsylvania) | 147.43 mi (237.26 km) |
| Syosset to Erie (Colorado) | 1,650.62 mi (2,656.42 km) |
| Syosset to Erie (Pennsylvania) | 351.80 mi (566.17 km) |
| Syosset to Erlanger (Kentucky) | 600.07 mi (965.72 km) |
| Syosset to Escanaba (Michigan) | 762.34 mi (1,226.87 km) |
| Syosset to Escondido (California) | 2,436.86 mi (3,921.75 km) |
| Syosset to Española (New Mexico) | 1,783.59 mi (2,870.40 km) |
| Syosset to Essex (Maryland) | 187.49 mi (301.73 km) |
| Syosset to Essex Junction (Vermont) | 254.65 mi (409.81 km) |
| Syosset to Estelle (Louisiana) | 1,200.58 mi (1,932.15 km) |
| Syosset to Estero (Florida) | 1,101.37 mi (1,772.49 km) |
| Syosset to Euclid (Ohio) | 420.01 mi (675.95 km) |
| Syosset to Eufaula (Alabama) | 892.15 mi (1,435.77 km) |
