| Sycamore to Sunset (Florida) | 1,221.24 mi (1,965.40 km) |
| Sycamore to Superior (Colorado) | 869.95 mi (1,400.05 km) |
| Sycamore to Superior (Wisconsin) | 365.44 mi (588.12 km) |
| Sycamore to Surprise (Arizona) | 1,412.35 mi (2,272.96 km) |
| Sycamore to Susanville (California) | 1,653.73 mi (2,661.42 km) |
| Sycamore to Sussex (Wisconsin) | 82.09 mi (132.11 km) |
| Sycamore to Suwanee (Georgia) | 603.40 mi (971.08 km) |
| Sycamore to Swansea (Illinois) | 247.74 mi (398.70 km) |
| Sycamore to Sweetwater (Florida) | 1,216.05 mi (1,957.05 km) |
| Sycamore to Sweetwater (Texas) | 919.93 mi (1,480.49 km) |
| Sycamore to Sylacauga (Alabama) | 623.43 mi (1,003.31 km) |
| Sycamore to Sylvania (Ohio) | 256.65 mi (413.04 km) |
| Sycamore to Syosset (New York) | 789.84 mi (1,271.13 km) |
| Sycamore to Syracuse (New York) | 641.99 mi (1,033.18 km) |
| Sycamore to Syracuse (Utah) | 1,207.37 mi (1,943.08 km) |
