| Sun City Center to Southchase (Florida) | 74.70 mi (120.23 km) |
| Sun City Center to Southern Pines (North Carolina) | 545.10 mi (877.26 km) |
| Sun City Center to Southfield (Michigan) | 1,021.18 mi (1,643.43 km) |
| Sun City Center to Southgate (Michigan) | 1,002.28 mi (1,613.01 km) |
| Sun City Center to Southlake (Texas) | 952.42 mi (1,532.77 km) |
| Sun City Center to Spanaway (Washington) | 2,535.03 mi (4,079.74 km) |
| Sun City Center to Spanish Fork (Utah) | 1,872.82 mi (3,014.00 km) |
| Sun City Center to Spanish Lake (Missouri) | 888.58 mi (1,430.04 km) |
| Sun City Center to Spanish Springs (Nevada) | 2,278.61 mi (3,667.07 km) |
| Sun City Center to Sparks (Nevada) | 2,280.11 mi (3,669.48 km) |
| Sun City Center to Spartanburg (South Carolina) | 500.14 mi (804.89 km) |
| Sun City Center to Spearfish (South Dakota) | 1,657.07 mi (2,666.80 km) |
| Sun City Center to Speedway (Indiana) | 863.72 mi (1,390.02 km) |
| Sun City Center to Spencer (Iowa) | 1,283.43 mi (2,065.48 km) |
| Sun City Center to Spokane (Washington) | 2,330.21 mi (3,750.11 km) |
