| Sumter to University Place (Washington) | 2,359.88 mi (3,797.85 km) |
| Sumter to Upland (California) | 2,121.92 mi (3,414.90 km) |
| Sumter to Upper Arlington (Ohio) | 445.78 mi (717.41 km) |
| Sumter to Upper Grand Lagoon (Florida) | 407.22 mi (655.36 km) |
| Sumter to Upper Montclair (New Jersey) | 585.39 mi (942.10 km) |
| Sumter to Urbana (Illinois) | 605.45 mi (974.38 km) |
| Sumter to Urbana (Maryland) | 408.84 mi (657.97 km) |
| Sumter to Urbana (Ohio) | 464.73 mi (747.92 km) |
| Sumter to Urbandale (Iowa) | 902.36 mi (1,452.21 km) |
| Sumter to Utica (New York) | 691.24 mi (1,112.44 km) |
| Sumter to Uvalde (Texas) | 1,184.72 mi (1,906.63 km) |
| Sumter to Vacaville (California) | 2,319.89 mi (3,733.50 km) |
| Sumter to Vadnais Heights (Minnesota) | 1,020.84 mi (1,642.88 km) |
| Sumter to Vail (Arizona) | 1,754.85 mi (2,824.16 km) |
| Sumter to Valdosta (Georgia) | 271.81 mi (437.43 km) |
