| Sumter to Superior (Colorado) | 1,423.73 mi (2,291.27 km) |
| Sumter to Superior (Wisconsin) | 1,072.55 mi (1,726.11 km) |
| Sumter to Surprise (Arizona) | 1,832.93 mi (2,949.81 km) |
| Sumter to Susanville (California) | 2,238.99 mi (3,603.31 km) |
| Sumter to Sussex (Wisconsin) | 762.55 mi (1,227.21 km) |
| Sumter to Suwanee (Georgia) | 210.68 mi (339.06 km) |
| Sumter to Swansea (Illinois) | 621.79 mi (1,000.67 km) |
| Sumter to Sweetwater (Florida) | 563.85 mi (907.43 km) |
| Sumter to Sweetwater (Texas) | 1,159.78 mi (1,866.49 km) |
| Sumter to Sycamore (Illinois) | 715.99 mi (1,152.27 km) |
| Sumter to Sylacauga (Alabama) | 341.85 mi (550.16 km) |
| Sumter to Sylvania (Ohio) | 566.47 mi (911.64 km) |
| Sumter to Syosset (New York) | 606.92 mi (976.74 km) |
| Sumter to Syracuse (New York) | 669.28 mi (1,077.10 km) |
| Sumter to Syracuse (Utah) | 1,793.90 mi (2,887.00 km) |
