| Sumter to Siloam Springs (Arkansas) | 813.73 mi (1,309.57 km) |
| Sumter to Silver Firs (Washington) | 2,347.83 mi (3,778.47 km) |
| Sumter to Silver Spring (Maryland) | 396.80 mi (638.58 km) |
| Sumter to Silver Springs Shores (Florida) | 346.88 mi (558.25 km) |
| Sumter to Silverdale (Washington) | 2,370.36 mi (3,814.73 km) |
| Sumter to Silverton (Oregon) | 2,355.98 mi (3,791.59 km) |
| Sumter to Simi Valley (California) | 2,181.25 mi (3,510.39 km) |
| Sumter to Simpsonville (South Carolina) | 119.52 mi (192.34 km) |
| Sumter to Sioux City (Iowa) | 1,047.73 mi (1,686.16 km) |
| Sumter to Sioux Falls (South Dakota) | 1,099.04 mi (1,768.74 km) |
| Sumter to Skokie (Illinois) | 687.17 mi (1,105.89 km) |
| Sumter to Sleepy Hollow (New York) | 609.55 mi (980.97 km) |
| Sumter to Slidell (Louisiana) | 604.28 mi (972.50 km) |
| Sumter to Smithfield (North Carolina) | 159.04 mi (255.94 km) |
| Sumter to Smithfield (Utah) | 1,787.26 mi (2,876.32 km) |
