| Street to San Luis Obispo (California) | 5,383.01 mi (8,663.12 km) |
| Street to San Marcos (California) | 5,388.44 mi (8,671.86 km) |
| Street to San Marcos (Texas) | 4,851.53 mi (7,807.79 km) |
| Street to San Marino (California) | 5,364.44 mi (8,633.24 km) |
| Street to San Mateo (California) | 5,304.14 mi (8,536.20 km) |
| Street to San Pablo (California) | 5,281.59 mi (8,499.90 km) |
| Street to San Rafael (California) | 5,285.49 mi (8,506.18 km) |
| Street to San Ramon (California) | 5,280.58 mi (8,498.28 km) |
| Street to San Tan Valley (Arizona) | 5,191.39 mi (8,354.73 km) |
| Street to Sand Springs (Oklahoma) | 4,462.70 mi (7,182.02 km) |
| Street to Sandusky (Ohio) | 3,684.32 mi (5,929.33 km) |
| Street to Sandy (Oregon) | 4,857.35 mi (7,817.15 km) |
| Street to Sandy (Utah) | 4,801.91 mi (7,727.92 km) |
| Street to Sandy Springs (Georgia) | 4,097.90 mi (6,594.94 km) |
| Street to Sanford (Florida) | 4,217.33 mi (6,787.13 km) |
