| Staten Island to Scottsbluff (Nebraska) | 1,528.64 mi (2,460.11 km) |
| Staten Island to Scottsboro (Alabama) | 768.74 mi (1,237.17 km) |
| Staten Island to Scottsdale (Arizona) | 2,114.36 mi (3,402.73 km) |
| Staten Island to Scranton (Pennsylvania) | 97.27 mi (156.55 km) |
| Staten Island to Seabrook (Maryland) | 181.18 mi (291.58 km) |
| Staten Island to Seabrook (Texas) | 1,398.49 mi (2,250.65 km) |
| Staten Island to Seaford (New York) | 34.96 mi (56.27 km) |
| Staten Island to Seagoville (Texas) | 1,352.48 mi (2,176.60 km) |
| Staten Island to Seal Beach (California) | 2,437.99 mi (3,923.57 km) |
| Staten Island to Searcy (Arkansas) | 1,024.95 mi (1,649.50 km) |
| Staten Island to Seaside (California) | 2,557.11 mi (4,115.26 km) |
| Staten Island to SeaTac (Washington) | 2,399.22 mi (3,861.17 km) |
| Staten Island to Seattle (Washington) | 2,399.01 mi (3,860.84 km) |
| Staten Island to Sebastian (Florida) | 954.96 mi (1,536.86 km) |
| Staten Island to Sebring (Florida) | 996.52 mi (1,603.74 km) |
