| State College to Storm Lake (Iowa) | 901.74 mi (1,451.20 km) |
| State College to Storrs (Connecticut) | 299.27 mi (481.62 km) |
| State College to Stoughton (Wisconsin) | 602.65 mi (969.87 km) |
| State College to Stow (Ohio) | 188.48 mi (303.34 km) |
| State College to Streamwood (Illinois) | 541.24 mi (871.04 km) |
| State College to Streator (Illinois) | 572.64 mi (921.58 km) |
| State College to Streetsboro (Ohio) | 184.50 mi (296.92 km) |
| State College to Strongsville (Ohio) | 210.19 mi (338.27 km) |
| State College to Stuart (Florida) | 949.12 mi (1,527.46 km) |
| State College to Stuarts Draft (Virginia) | 201.60 mi (324.44 km) |
| State College to Sturgis (Michigan) | 398.53 mi (641.38 km) |
| State College to Suamico (Wisconsin) | 581.91 mi (936.50 km) |
| State College to Sudley (Virginia) | 139.72 mi (224.85 km) |
| State College to Suffern (New York) | 195.10 mi (313.98 km) |
| State College to Suffolk (Virginia) | 290.47 mi (467.46 km) |
