| State College to Stephenville (Texas) | 1,272.45 mi (2,047.81 km) |
| State College to Sterling (Colorado) | 1,322.43 mi (2,128.25 km) |
| State College to Sterling (Illinois) | 618.01 mi (994.59 km) |
| State College to Sterling (Virginia) | 125.68 mi (202.26 km) |
| State College to Sterling Heights (Michigan) | 294.15 mi (473.39 km) |
| State College to Steubenville (Ohio) | 149.60 mi (240.75 km) |
| State College to Stevens Point (Wisconsin) | 646.99 mi (1,041.23 km) |
| State College to Stevenson Ranch (California) | 2,252.61 mi (3,625.23 km) |
| State College to Stillwater (Minnesota) | 811.43 mi (1,305.87 km) |
| State College to Stillwater (Oklahoma) | 1,085.80 mi (1,747.42 km) |
| State College to Stockbridge (Georgia) | 612.09 mi (985.06 km) |
| State College to Stockton (California) | 2,304.99 mi (3,709.52 km) |
| State College to Stone Ridge (Virginia) | 129.60 mi (208.58 km) |
| State College to Stonecrest (Georgia) | 600.00 mi (965.60 km) |
| State College to Stony Brook (New York) | 247.25 mi (397.92 km) |
