| State College to Smithville (Missouri) | 887.58 mi (1,428.42 km) |
| State College to Smyrna (Delaware) | 157.62 mi (253.67 km) |
| State College to Smyrna (Georgia) | 602.08 mi (968.95 km) |
| State College to Smyrna (Tennessee) | 575.30 mi (925.86 km) |
| State College to Snellville (Georgia) | 585.86 mi (942.85 km) |
| State College to Snoqualmie (Washington) | 2,198.51 mi (3,538.16 km) |
| State College to Snyder (Texas) | 1,387.55 mi (2,233.05 km) |
| State College to Socastee (South Carolina) | 494.88 mi (796.44 km) |
| State College to Socorro (Texas) | 1,695.52 mi (2,728.68 km) |
| State College to Soddy-Daisy (Tennessee) | 551.70 mi (887.88 km) |
| State College to Solana Beach (California) | 2,222.99 mi (3,577.56 km) |
| State College to Soledad (California) | 2,342.59 mi (3,770.04 km) |
| State College to Solon (Ohio) | 191.07 mi (307.50 km) |
| State College to Somers Point (New Jersey) | 199.78 mi (321.51 km) |
| State College to Somerset (Kentucky) | 444.06 mi (714.64 km) |
