| State College to Siloam Springs (Arkansas) | 954.50 mi (1,536.11 km) |
| State College to Silver Firs (Washington) | 2,211.16 mi (3,558.53 km) |
| State College to Silver Spring (Maryland) | 131.25 mi (211.23 km) |
| State College to Silver Springs Shores (Florida) | 840.27 mi (1,352.28 km) |
| State College to Silverdale (Washington) | 2,236.87 mi (3,599.90 km) |
| State College to Silverton (Oregon) | 2,263.03 mi (3,642.00 km) |
| State College to Simi Valley (California) | 2,264.42 mi (3,644.23 km) |
| State College to Simpsonville (South Carolina) | 482.75 mi (776.92 km) |
| State College to Sioux City (Iowa) | 962.20 mi (1,548.52 km) |
| State College to Sioux Falls (South Dakota) | 982.83 mi (1,581.72 km) |
| State College to Skokie (Illinois) | 518.99 mi (835.23 km) |
| State College to Sleepy Hollow (New York) | 208.99 mi (336.33 km) |
| State College to Slidell (Louisiana) | 986.09 mi (1,586.97 km) |
| State College to Smithfield (North Carolina) | 365.63 mi (588.42 km) |
| State College to Smithfield (Utah) | 1,752.88 mi (2,820.99 km) |
