| State College to Seymour (Indiana) | 444.50 mi (715.35 km) |
| State College to Seymour (Tennessee) | 466.47 mi (750.72 km) |
| State College to Shady Hills (Florida) | 896.06 mi (1,442.07 km) |
| State College to Shafter (California) | 2,255.49 mi (3,629.86 km) |
| State College to Shaker Heights (Ohio) | 197.88 mi (318.46 km) |
| State College to Shakopee (Minnesota) | 836.96 mi (1,346.96 km) |
| State College to Sharon (Pennsylvania) | 141.15 mi (227.16 km) |
| State College to Sharonville (Ohio) | 361.75 mi (582.17 km) |
| State College to Shasta Lake (California) | 2,305.10 mi (3,709.71 km) |
| State College to Shawnee (Kansas) | 905.33 mi (1,457.00 km) |
| State College to Shawnee (Oklahoma) | 1,102.38 mi (1,774.11 km) |
| State College to Sheboygan (Wisconsin) | 544.05 mi (875.56 km) |
| State College to Shelby (North Carolina) | 429.68 mi (691.51 km) |
| State College to Shelbyville (Indiana) | 427.07 mi (687.30 km) |
| State College to Shelbyville (Kentucky) | 431.53 mi (694.47 km) |
