| State College to Olympia (Washington) | 2,250.69 mi (3,622.14 km) |
| State College to Olympia Heights (Florida) | 1,050.72 mi (1,690.98 km) |
| State College to Omaha (Nebraska) | 947.29 mi (1,524.51 km) |
| State College to On Top of the World Designated Place (Florida) | 845.12 mi (1,360.09 km) |
| State College to Onalaska (Wisconsin) | 713.69 mi (1,148.58 km) |
| State College to Oneida (New York) | 194.07 mi (312.33 km) |
| State College to Oneonta (New York) | 184.34 mi (296.67 km) |
| State College to Ontario (California) | 2,211.01 mi (3,558.28 km) |
| State College to Ontario (Oregon) | 1,989.31 mi (3,201.49 km) |
| State College to Opa-locka (Florida) | 1,038.03 mi (1,670.55 km) |
| State College to Opelika (Alabama) | 698.63 mi (1,124.34 km) |
| State College to Opelousas (Louisiana) | 1,065.53 mi (1,714.80 km) |
| State College to Orange (California) | 2,228.94 mi (3,587.13 km) |
| State College to Orange (Texas) | 1,156.25 mi (1,860.80 km) |
| State College to Orange City (Florida) | 841.76 mi (1,354.68 km) |
