| Spondon to Southern Pines (North Carolina) | 3,854.80 mi (6,203.70 km) |
| Spondon to Southfield (Michigan) | 3,662.47 mi (5,894.17 km) |
| Spondon to Southgate (Michigan) | 3,672.87 mi (5,910.92 km) |
| Spondon to Southlake (Texas) | 4,661.17 mi (7,501.42 km) |
| Spondon to Spanaway (Washington) | 4,705.76 mi (7,573.20 km) |
| Spondon to Spanish Fork (Utah) | 4,783.99 mi (7,699.09 km) |
| Spondon to Spanish Lake (Missouri) | 4,101.75 mi (6,601.12 km) |
| Spondon to Spanish Springs (Nevada) | 5,056.51 mi (8,137.66 km) |
| Spondon to Sparks (Nevada) | 5,062.67 mi (8,147.58 km) |
| Spondon to Spartanburg (South Carolina) | 3,968.05 mi (6,385.96 km) |
| Spondon to Spearfish (South Dakota) | 4,296.53 mi (6,914.60 km) |
| Spondon to Speedway (Indiana) | 3,902.45 mi (6,280.38 km) |
| Spondon to Spencer (Iowa) | 4,068.37 mi (6,547.41 km) |
| Spondon to Spokane (Washington) | 4,539.20 mi (7,305.14 km) |
| Spondon to Spokane Valley (Washington) | 4,533.96 mi (7,296.70 km) |
