| Spitalfields to Shoreham-by-Sea | 47.94 mi (77.15 km) |
| Spitalfields to Shotley Bridge | 243.17 mi (391.35 km) |
| Spitalfields to Shrewsbury | 140.33 mi (225.85 km) |
| Spitalfields to Sidcup | 9.86 mi (15.87 km) |
| Spitalfields to Sidmouth | 148.94 mi (239.70 km) |
| Spitalfields to Sileby | 94.62 mi (152.27 km) |
| Spitalfields to Sittingbourne | 37.17 mi (59.82 km) |
| Spitalfields to Skegness | 113.79 mi (183.13 km) |
| Spitalfields to Skelmersdale | 180.60 mi (290.65 km) |
| Spitalfields to Skipton | 187.48 mi (301.71 km) |
| Spitalfields to Sleaford | 103.21 mi (166.10 km) |
| Spitalfields to Slough | 22.07 mi (35.52 km) |
| Spitalfields to Small Heath | 100.02 mi (160.97 km) |
| Spitalfields to Smethwick | 105.06 mi (169.08 km) |
| Spitalfields to Snaresbrook | 6.20 mi (9.98 km) |
