| Spanish Lake to Scottsbluff (Nebraska) | 739.01 mi (1,189.32 km) |
| Spanish Lake to Scottsboro (Alabama) | 367.40 mi (591.28 km) |
| Spanish Lake to Scottsdale (Arizona) | 1,253.91 mi (2,017.98 km) |
| Spanish Lake to Scranton (Pennsylvania) | 788.57 mi (1,269.08 km) |
| Spanish Lake to Seabrook (Maryland) | 717.89 mi (1,155.33 km) |
| Spanish Lake to Seabrook (Texas) | 693.25 mi (1,115.68 km) |
| Spanish Lake to Seaford (New York) | 896.28 mi (1,442.43 km) |
| Spanish Lake to Seagoville (Texas) | 552.95 mi (889.88 km) |
| Spanish Lake to Seal Beach (California) | 1,584.06 mi (2,549.29 km) |
| Spanish Lake to Searcy (Arkansas) | 259.12 mi (417.01 km) |
| Spanish Lake to Seaside (California) | 1,725.92 mi (2,777.61 km) |
| Spanish Lake to SeaTac (Washington) | 1,710.81 mi (2,753.28 km) |
| Spanish Lake to Seattle (Washington) | 1,713.87 mi (2,758.20 km) |
| Spanish Lake to Sebastian (Florida) | 944.14 mi (1,519.44 km) |
| Spanish Lake to Sebring (Florida) | 930.24 mi (1,497.07 km) |
