| Spa to Southern Pines (North Carolina) | 4,202.28 mi (6,762.92 km) |
| Spa to Southfield (Michigan) | 4,015.52 mi (6,462.36 km) |
| Spa to Southgate (Michigan) | 4,025.88 mi (6,479.03 km) |
| Spa to Southlake (Texas) | 5,014.34 mi (8,069.80 km) |
| Spa to Spanaway (Washington) | 5,025.34 mi (8,087.51 km) |
| Spa to Spanish Fork (Utah) | 5,126.35 mi (8,250.07 km) |
| Spa to Spanish Lake (Missouri) | 4,454.91 mi (7,169.49 km) |
| Spa to Spanish Springs (Nevada) | 5,389.99 mi (8,674.35 km) |
| Spa to Sparks (Nevada) | 5,396.18 mi (8,684.31 km) |
| Spa to Spartanburg (South Carolina) | 4,317.04 mi (6,947.60 km) |
| Spa to Spearfish (South Dakota) | 4,641.58 mi (7,469.91 km) |
| Spa to Speedway (Indiana) | 4,255.40 mi (6,848.41 km) |
| Spa to Spencer (Iowa) | 4,419.52 mi (7,112.53 km) |
| Spa to Spokane (Washington) | 4,865.40 mi (7,830.10 km) |
| Spa to Spokane Valley (Washington) | 4,860.44 mi (7,822.12 km) |
