| Southborough to Stephenville (Texas) | 4,857.96 mi (7,818.13 km) |
| Southborough to Sterling (Colorado) | 4,605.22 mi (7,411.38 km) |
| Southborough to Sterling (Illinois) | 4,055.97 mi (6,527.46 km) |
| Southborough to Sterling (Virginia) | 3,699.07 mi (5,953.07 km) |
| Southborough to Sterling Heights (Michigan) | 3,764.44 mi (6,058.29 km) |
| Southborough to Steubenville (Ohio) | 3,769.52 mi (6,066.45 km) |
| Southborough to Stevens Point (Wisconsin) | 3,924.29 mi (6,315.54 km) |
| Southborough to Stevenson Ranch (California) | 5,460.89 mi (8,788.45 km) |
| Southborough to Stillwater (Minnesota) | 4,019.24 mi (6,468.34 km) |
| Southborough to Stillwater (Oklahoma) | 4,612.75 mi (7,423.50 km) |
| Southborough to Stockbridge (Georgia) | 4,234.85 mi (6,815.34 km) |
| Southborough to Stockton (California) | 5,338.57 mi (8,591.59 km) |
| Southborough to Stone Ridge (Virginia) | 3,708.63 mi (5,968.46 km) |
| Southborough to Stonecrest (Georgia) | 4,223.37 mi (6,796.86 km) |
| Southborough to Stony Brook (New York) | 3,440.59 mi (5,537.09 km) |
