| Southborough to St. George (Utah) | 5,147.06 mi (8,283.40 km) |
| Southborough to St. Helens (Oregon) | 4,926.68 mi (7,928.73 km) |
| Southborough to St. James (New York) | 3,442.86 mi (5,540.75 km) |
| Southborough to St. John (Indiana) | 3,987.81 mi (6,417.75 km) |
| Southborough to St. Joseph (Missouri) | 4,346.53 mi (6,995.06 km) |
| Southborough to St. Louis (Missouri) | 4,227.59 mi (6,803.65 km) |
| Southborough to St. Louis Park (Minnesota) | 4,043.49 mi (6,507.37 km) |
| Southborough to St. Marys (Georgia) | 4,259.66 mi (6,855.26 km) |
| Southborough to St. Marys (Pennsylvania) | 3,636.29 mi (5,852.04 km) |
| Southborough to St. Matthews (Kentucky) | 4,065.63 mi (6,543.00 km) |
| Southborough to St. Michael (Minnesota) | 4,043.34 mi (6,507.13 km) |
| Southborough to St. Paul (Minnesota) | 4,034.16 mi (6,492.35 km) |
| Southborough to St. Peter (Minnesota) | 4,094.29 mi (6,589.12 km) |
| Southborough to St. Peters (Missouri) | 4,234.44 mi (6,814.67 km) |
| Southborough to St. Petersburg (Florida) | 4,452.33 mi (7,165.33 km) |
