| Southborough to Spout Springs (North Carolina) | 3,937.25 mi (6,336.39 km) |
| Southborough to Spring (Texas) | 4,858.72 mi (7,819.35 km) |
| Southborough to Spring Creek (Nevada) | 5,007.58 mi (8,058.93 km) |
| Southborough to Spring Hill (Florida) | 4,412.35 mi (7,101.00 km) |
| Southborough to Spring Hill (Tennessee) | 4,236.10 mi (6,817.34 km) |
| Southborough to Spring Lake (North Carolina) | 3,939.85 mi (6,340.58 km) |
| Southborough to Spring Valley (California) | 5,503.27 mi (8,856.66 km) |
| Southborough to Spring Valley (Nevada) | 5,256.99 mi (8,460.32 km) |
| Southborough to Spring Valley (New York) | 3,469.41 mi (5,583.48 km) |
| Southborough to Springboro (Ohio) | 3,948.76 mi (6,354.91 km) |
| Southborough to Springdale (Arkansas) | 4,498.64 mi (7,239.87 km) |
| Southborough to Springdale (New Jersey) | 3,560.80 mi (5,730.56 km) |
| Southborough to Springdale (Ohio) | 3,970.84 mi (6,390.45 km) |
| Southborough to Springfield (Illinois) | 4,150.37 mi (6,679.37 km) |
| Southborough to Springfield (Massachusetts) | 3,365.47 mi (5,416.21 km) |
