| Southborough to Somersworth (New Hampshire) | 3,251.19 mi (5,232.29 km) |
| Southborough to Somerton (Arizona) | 5,434.74 mi (8,746.37 km) |
| Southborough to Somerville (Massachusetts) | 3,295.20 mi (5,303.11 km) |
| Southborough to Somerville (New Jersey) | 3,515.80 mi (5,658.14 km) |
| Southborough to Sonoma (California) | 5,354.36 mi (8,617.00 km) |
| Southborough to Soquel (California) | 5,414.31 mi (8,713.49 km) |
| Southborough to South Bend (Indiana) | 3,930.84 mi (6,326.07 km) |
| Southborough to South Bradenton (Florida) | 4,465.44 mi (7,186.43 km) |
| Southborough to South Burlington (Vermont) | 3,296.85 mi (5,305.77 km) |
| Southborough to South Charleston (West Virginia) | 3,904.33 mi (6,283.41 km) |
| Southborough to South Daytona (Florida) | 4,314.09 mi (6,942.86 km) |
| Southborough to South El Monte (California) | 5,463.04 mi (8,791.91 km) |
| Southborough to South Elgin (Illinois) | 3,994.64 mi (6,428.76 km) |
| Southborough to South Euclid (Ohio) | 3,752.40 mi (6,038.91 km) |
| Southborough to South Farmingdale (New York) | 3,461.77 mi (5,571.19 km) |
