| Southborough to Shoreview (Minnesota) | 4,028.92 mi (6,483.92 km) |
| Southborough to Shorewood (Illinois) | 4,012.90 mi (6,458.14 km) |
| Southborough to Shorewood (Wisconsin) | 3,927.70 mi (6,321.02 km) |
| Southborough to Short Hills (New Jersey) | 3,496.98 mi (5,627.84 km) |
| Southborough to Short Pump (Virginia) | 3,768.83 mi (6,065.34 km) |
| Southborough to Show Low (Arizona) | 5,182.42 mi (8,340.30 km) |
| Southborough to Shreveport (Louisiana) | 4,672.58 mi (7,519.79 km) |
| Southborough to Sicklerville (New Jersey) | 3,567.42 mi (5,741.22 km) |
| Southborough to Sidney (Ohio) | 3,912.55 mi (6,296.63 km) |
| Southborough to Sierra Madre (California) | 5,456.28 mi (8,781.04 km) |
| Southborough to Sierra Vista (Arizona) | 5,340.86 mi (8,595.29 km) |
| Southborough to Sierra Vista Southeast (Arizona) | 5,343.44 mi (8,599.43 km) |
| Southborough to Signal Hill (California) | 5,480.97 mi (8,820.78 km) |
| Southborough to Sikeston (Missouri) | 4,286.82 mi (6,898.96 km) |
| Southborough to Siloam Springs (Arkansas) | 4,513.29 mi (7,263.44 km) |
