| Southborough to Security-Widefield (Colorado) | 4,755.86 mi (7,653.81 km) |
| Southborough to Sedalia (Missouri) | 4,338.64 mi (6,982.37 km) |
| Southborough to Sedro-Woolley (Washington) | 4,759.47 mi (7,659.63 km) |
| Southborough to Seguin (Texas) | 4,985.16 mi (8,022.83 km) |
| Southborough to Selden (New York) | 3,438.73 mi (5,534.10 km) |
| Southborough to Selma (Alabama) | 4,403.79 mi (7,087.21 km) |
| Southborough to Selma (California) | 5,367.99 mi (8,638.94 km) |
| Southborough to Selma (Texas) | 4,998.81 mi (8,044.82 km) |
| Southborough to Seminole (Florida) | 4,454.81 mi (7,169.33 km) |
| Southborough to Seven Hills (Ohio) | 3,764.71 mi (6,058.72 km) |
| Southborough to Seven Oaks (South Carolina) | 4,082.61 mi (6,570.32 km) |
| Southborough to Severn (Maryland) | 3,664.21 mi (5,896.97 km) |
| Southborough to Severna Park (Maryland) | 3,661.16 mi (5,892.07 km) |
| Southborough to Sevierville (Tennessee) | 4,094.36 mi (6,589.23 km) |
| Southborough to Seymour (Indiana) | 4,042.79 mi (6,506.25 km) |
