| Southborough to Savannah (Georgia) | 4,181.37 mi (6,729.26 km) |
| Southborough to Sayreville (New Jersey) | 3,508.59 mi (5,646.53 km) |
| Southborough to Sayville (New York) | 3,445.54 mi (5,545.06 km) |
| Southborough to Scaggsville (Maryland) | 3,671.66 mi (5,908.97 km) |
| Southborough to Scarsdale (New York) | 3,463.65 mi (5,574.20 km) |
| Southborough to Schaumburg (Illinois) | 3,984.04 mi (6,411.69 km) |
| Southborough to Schenectady (New York) | 3,393.30 mi (5,460.99 km) |
| Southborough to Schererville (Indiana) | 3,984.82 mi (6,412.96 km) |
| Southborough to Schertz (Texas) | 4,997.61 mi (8,042.88 km) |
| Southborough to Schiller Park (Illinois) | 3,979.21 mi (6,403.91 km) |
| Southborough to Schofield Barracks (Hawaii) | 7,246.93 mi (11,662.80 km) |
| Southborough to Scotchtown (New York) | 3,466.99 mi (5,579.58 km) |
| Southborough to Scottdale (Georgia) | 4,223.17 mi (6,796.54 km) |
| Southborough to Scotts Valley (California) | 5,412.86 mi (8,711.15 km) |
| Southborough to Scottsbluff (Nebraska) | 4,557.07 mi (7,333.90 km) |
