| Southborough to Sanford (Maine) | 3,239.06 mi (5,212.76 km) |
| Southborough to Sanford (North Carolina) | 3,933.14 mi (6,329.78 km) |
| Southborough to Sanger (California) | 5,358.92 mi (8,624.35 km) |
| Southborough to Santa Ana (California) | 5,475.52 mi (8,812.00 km) |
| Southborough to Santa Barbara (California) | 5,494.52 mi (8,842.57 km) |
| Southborough to Santa Clara (California) | 5,393.60 mi (8,680.16 km) |
| Southborough to Santa Clara (Oregon) | 5,035.66 mi (8,104.11 km) |
| Southborough to Santa Clarita (California) | 5,456.35 mi (8,781.14 km) |
| Southborough to Santa Cruz (California) | 5,417.99 mi (8,719.41 km) |
| Southborough to Santa Fe (New Mexico) | 4,964.22 mi (7,989.14 km) |
| Southborough to Santa Fe (Texas) | 4,882.29 mi (7,857.29 km) |
| Southborough to Santa Fe Springs (California) | 5,470.15 mi (8,803.35 km) |
| Southborough to Santa Maria (California) | 5,488.01 mi (8,832.09 km) |
| Southborough to Santa Monica (California) | 5,478.41 mi (8,816.65 km) |
| Southborough to Santa Paula (California) | 5,478.08 mi (8,816.11 km) |
