| Southborough to Saddlebrooke (Arizona) | 5,305.63 mi (8,538.58 km) |
| Southborough to Safety Harbor (Florida) | 4,442.90 mi (7,150.15 km) |
| Southborough to Saginaw (Michigan) | 3,762.78 mi (6,055.61 km) |
| Southborough to Saginaw (Texas) | 4,791.28 mi (7,710.82 km) |
| Southborough to Sahuarita (Arizona) | 5,343.40 mi (8,599.37 km) |
| Southborough to Saks (Alabama) | 4,292.11 mi (6,907.49 km) |
| Southborough to Salem (Massachusetts) | 3,282.02 mi (5,281.89 km) |
| Southborough to Salem (Ohio) | 3,753.23 mi (6,040.23 km) |
| Southborough to Salem (Oregon) | 4,986.03 mi (8,024.25 km) |
| Southborough to Salem (Virginia) | 3,885.64 mi (6,253.34 km) |
| Southborough to Salem Lakes (Wisconsin) | 3,962.44 mi (6,376.93 km) |
| Southborough to Salida (California) | 5,347.28 mi (8,605.62 km) |
| Southborough to Salina (Kansas) | 4,497.20 mi (7,237.55 km) |
| Southborough to Salinas (California) | 5,422.78 mi (8,727.11 km) |
| Southborough to Salisbury (Maryland) | 3,652.45 mi (5,878.05 km) |
