| Southborough to Reidsville (North Carolina) | 3,913.92 mi (6,298.85 km) |
| Southborough to Reisterstown (Maryland) | 3,654.85 mi (5,881.91 km) |
| Southborough to Rendon (Texas) | 4,801.06 mi (7,726.56 km) |
| Southborough to Reno (Nevada) | 5,204.42 mi (8,375.71 km) |
| Southborough to Renton (Washington) | 4,817.27 mi (7,752.65 km) |
| Southborough to Republic (Missouri) | 4,423.68 mi (7,119.23 km) |
| Southborough to Reston (Virginia) | 3,699.14 mi (5,953.19 km) |
| Southborough to Revere (Massachusetts) | 3,290.05 mi (5,294.83 km) |
| Southborough to Rexburg (Idaho) | 4,720.51 mi (7,596.92 km) |
| Southborough to Reynoldsburg (Ohio) | 3,873.36 mi (6,233.58 km) |
| Southborough to Rialto (California) | 5,437.86 mi (8,751.39 km) |
| Southborough to Richardson (Texas) | 4,760.49 mi (7,661.27 km) |
| Southborough to Richfield (Minnesota) | 4,043.95 mi (6,508.10 km) |
| Southborough to Richfield (Wisconsin) | 3,934.40 mi (6,331.80 km) |
| Southborough to Richland (Washington) | 4,806.52 mi (7,735.35 km) |
