| Southborough to Indianola (Iowa) | 4,221.65 mi (6,794.09 km) |
| Southborough to Indio (California) | 5,421.89 mi (8,725.70 km) |
| Southborough to Inglewood (California) | 5,477.86 mi (8,815.76 km) |
| Southborough to Inkster (Michigan) | 3,788.33 mi (6,096.73 km) |
| Southborough to Inver Grove Heights (Minnesota) | 4,038.33 mi (6,499.07 km) |
| Southborough to Inwood (New York) | 3,478.33 mi (5,597.84 km) |
| Southborough to Iona (Florida) | 4,486.55 mi (7,220.40 km) |
| Southborough to Ionia (Michigan) | 3,825.69 mi (6,156.86 km) |
| Southborough to Iowa City (Iowa) | 4,131.79 mi (6,649.48 km) |
| Southborough to Irmo (South Carolina) | 4,082.17 mi (6,569.62 km) |
| Southborough to Irondale (Alabama) | 4,333.12 mi (6,973.48 km) |
| Southborough to Ironton (Ohio) | 3,934.30 mi (6,331.64 km) |
| Southborough to Irvine (California) | 5,475.42 mi (8,811.84 km) |
| Southborough to Irving (Texas) | 4,776.41 mi (7,686.89 km) |
| Southborough to Isabela (Puerto Rico) | 4,250.97 mi (6,841.27 km) |
