| Southborough to Friendswood (Texas) | 4,879.86 mi (7,853.38 km) |
| Southborough to Frisco (Texas) | 4,755.34 mi (7,652.98 km) |
| Southborough to Front Royal (Virginia) | 3,734.44 mi (6,009.99 km) |
| Southborough to Fruit Cove (Florida) | 4,293.93 mi (6,910.41 km) |
| Southborough to Fruita (Colorado) | 4,872.31 mi (7,841.22 km) |
| Southborough to Fruitville (Florida) | 4,466.78 mi (7,188.58 km) |
| Southborough to Fuller Heights (Florida) | 4,417.69 mi (7,109.58 km) |
| Southborough to Fullerton (California) | 5,468.59 mi (8,800.85 km) |
| Southborough to Fullerton (Pennsylvania) | 3,548.88 mi (5,711.38 km) |
| Southborough to Fulshear (Texas) | 4,897.51 mi (7,881.78 km) |
| Southborough to Fulton (Missouri) | 4,282.50 mi (6,892.02 km) |
| Southborough to Fulton (New York) | 3,471.82 mi (5,587.35 km) |
| Southborough to Fuquay-Varina (North Carolina) | 3,911.57 mi (6,295.07 km) |
| Southborough to Gadsden (Alabama) | 4,284.23 mi (6,894.80 km) |
| Southborough to Gaffney (South Carolina) | 4,054.83 mi (6,525.62 km) |
