| Southborough to Euless (Texas) | 4,781.04 mi (7,694.34 km) |
| Southborough to Eureka (California) | 5,256.89 mi (8,460.14 km) |
| Southborough to Eureka (Missouri) | 4,249.74 mi (6,839.29 km) |
| Southborough to Eustis (Florida) | 4,357.72 mi (7,013.07 km) |
| Southborough to Evans (Colorado) | 4,672.04 mi (7,518.92 km) |
| Southborough to Evans (Georgia) | 4,146.89 mi (6,673.77 km) |
| Southborough to Evanston (Illinois) | 3,968.47 mi (6,386.63 km) |
| Southborough to Evanston (Wyoming) | 4,832.60 mi (7,777.32 km) |
| Southborough to Evansville (Indiana) | 4,152.95 mi (6,683.53 km) |
| Southborough to Everett (Massachusetts) | 3,292.64 mi (5,298.99 km) |
| Southborough to Everett (Washington) | 4,789.59 mi (7,708.10 km) |
| Southborough to Evergreen Park (Illinois) | 3,983.78 mi (6,411.27 km) |
| Southborough to Ewa Beach (Hawaii) | 7,257.86 mi (11,680.40 km) |
| Southborough to Ewa Gentry (Hawaii) | 7,257.06 mi (11,679.11 km) |
| Southborough to Excelsior Springs (Missouri) | 4,345.50 mi (6,993.41 km) |
