| Southborough to El Sobrante (California) | 5,454.19 mi (8,777.68 km) |
| Southborough to Eldersburg (Maryland) | 3,662.78 mi (5,894.68 km) |
| Southborough to Elfers (Florida) | 4,433.73 mi (7,135.40 km) |
| Southborough to Elgin (Illinois) | 3,992.83 mi (6,425.84 km) |
| Southborough to Elizabeth (New Jersey) | 3,494.53 mi (5,623.90 km) |
| Southborough to Elizabeth City (North Carolina) | 3,773.64 mi (6,073.09 km) |
| Southborough to Elizabethton (Tennessee) | 4,018.96 mi (6,467.89 km) |
| Southborough to Elizabethtown (Kentucky) | 4,100.96 mi (6,599.86 km) |
| Southborough to Elizabethtown (Pennsylvania) | 3,615.23 mi (5,818.16 km) |
| Southborough to Elk City (Oklahoma) | 4,739.52 mi (7,627.53 km) |
| Southborough to Elk Grove (California) | 5,315.34 mi (8,554.21 km) |
| Southborough to Elk Grove Village (Illinois) | 3,981.67 mi (6,407.89 km) |
| Southborough to Elk Plain (Washington) | 4,846.77 mi (7,800.12 km) |
| Southborough to Elk River (Minnesota) | 4,032.78 mi (6,490.13 km) |
| Southborough to Elkhart (Indiana) | 3,918.31 mi (6,305.91 km) |
