| Southborough to Desert Hot Springs (California) | 5,419.53 mi (8,721.88 km) |
| Southborough to DeSoto (Texas) | 4,785.63 mi (7,701.73 km) |
| Southborough to Destin (Florida) | 4,481.11 mi (7,211.64 km) |
| Southborough to Destrehan (Louisiana) | 4,662.41 mi (7,503.42 km) |
| Southborough to Detroit (Michigan) | 3,776.04 mi (6,076.95 km) |
| Southborough to Diamond Bar (California) | 5,458.41 mi (8,784.46 km) |
| Southborough to Diamond Springs (California) | 5,283.22 mi (8,502.52 km) |
| Southborough to Dickinson (North Dakota) | 4,273.27 mi (6,877.16 km) |
| Southborough to Dickinson (Texas) | 4,877.23 mi (7,849.14 km) |
| Southborough to Dickson (Tennessee) | 4,238.80 mi (6,821.69 km) |
| Southborough to Difficult Run (Virginia) | 3,701.34 mi (5,956.73 km) |
| Southborough to Dinuba (California) | 5,362.82 mi (8,630.63 km) |
| Southborough to Discovery Bay (California) | 5,351.21 mi (8,611.94 km) |
| Southborough to Dix Hills (New York) | 3,453.59 mi (5,558.02 km) |
| Southborough to Dixon (California) | 5,326.60 mi (8,572.33 km) |
