| Southborough to Ansonia (Connecticut) | 3,419.55 mi (5,503.23 km) |
| Southborough to Antelope (California) | 5,297.37 mi (8,525.29 km) |
| Southborough to Anthem (Arizona) | 5,276.80 mi (8,492.19 km) |
| Southborough to Antioch (California) | 5,352.87 mi (8,614.61 km) |
| Southborough to Antioch (Illinois) | 3,963.10 mi (6,377.99 km) |
| Southborough to Apache Junction (Arizona) | 5,282.13 mi (8,500.76 km) |
| Southborough to Apex (North Carolina) | 3,909.58 mi (6,291.86 km) |
| Southborough to Apollo Beach (Florida) | 4,442.72 mi (7,149.86 km) |
| Southborough to Apopka (Florida) | 4,359.26 mi (7,015.56 km) |
| Southborough to Apple Valley (California) | 5,408.32 mi (8,703.85 km) |
| Southborough to Apple Valley (Minnesota) | 4,047.11 mi (6,513.19 km) |
| Southborough to Appleton (Wisconsin) | 3,892.43 mi (6,264.26 km) |
| Southborough to Arbutus (Maryland) | 3,659.29 mi (5,889.06 km) |
| Southborough to Arcadia (California) | 5,457.83 mi (8,783.53 km) |
| Southborough to Arcata (California) | 5,250.71 mi (8,450.21 km) |
