| Southaven to Superior (Colorado) | 899.60 mi (1,447.76 km) |
| Southaven to Superior (Wisconsin) | 818.68 mi (1,317.54 km) |
| Southaven to Surprise (Arizona) | 1,282.76 mi (2,064.40 km) |
| Southaven to Susanville (California) | 1,708.01 mi (2,748.78 km) |
| Southaven to Sussex (Wisconsin) | 573.16 mi (922.42 km) |
| Southaven to Suwanee (Georgia) | 342.17 mi (550.67 km) |
| Southaven to Swansea (Illinois) | 248.69 mi (400.22 km) |
| Southaven to Sweetwater (Florida) | 853.10 mi (1,372.93 km) |
| Southaven to Sweetwater (Texas) | 623.20 mi (1,002.95 km) |
| Southaven to Sycamore (Illinois) | 491.72 mi (791.35 km) |
| Southaven to Sylacauga (Alabama) | 245.54 mi (395.16 km) |
| Southaven to Sylvania (Ohio) | 577.15 mi (928.83 km) |
| Southaven to Syosset (New York) | 983.57 mi (1,582.90 km) |
| Southaven to Syracuse (New York) | 927.64 mi (1,492.90 km) |
| Southaven to Syracuse (Utah) | 1,270.76 mi (2,045.09 km) |
