| Southaven to Storm Lake (Iowa) | 600.83 mi (966.94 km) |
| Southaven to Storrs (Connecticut) | 1,067.87 mi (1,718.56 km) |
| Southaven to Stoughton (Wisconsin) | 552.32 mi (888.88 km) |
| Southaven to Stow (Ohio) | 632.67 mi (1,018.19 km) |
| Southaven to Streamwood (Illinois) | 498.03 mi (801.51 km) |
| Southaven to Streator (Illinois) | 431.07 mi (693.73 km) |
| Southaven to Streetsboro (Ohio) | 639.01 mi (1,028.39 km) |
| Southaven to Strongsville (Ohio) | 623.34 mi (1,003.16 km) |
| Southaven to Stuart (Florida) | 785.94 mi (1,264.85 km) |
| Southaven to Stuarts Draft (Virginia) | 643.31 mi (1,035.31 km) |
| Southaven to Sturgis (Michigan) | 533.52 mi (858.62 km) |
| Southaven to Suamico (Wisconsin) | 676.69 mi (1,089.02 km) |
| Southaven to Sudley (Virginia) | 738.35 mi (1,188.26 km) |
| Southaven to Suffern (New York) | 959.29 mi (1,543.83 km) |
| Southaven to Suffolk (Virginia) | 756.28 mi (1,217.12 km) |
