| Southaven to Siloam Springs (Arkansas) | 269.66 mi (433.97 km) |
| Southaven to Silver Firs (Washington) | 1,871.81 mi (3,012.38 km) |
| Southaven to Silver Spring (Maryland) | 767.17 mi (1,234.65 km) |
| Southaven to Silver Springs Shores (Florida) | 616.30 mi (991.85 km) |
| Southaven to Silverdale (Washington) | 1,891.81 mi (3,044.57 km) |
| Southaven to Silverton (Oregon) | 1,854.73 mi (2,984.90 km) |
| Southaven to Simi Valley (California) | 1,631.12 mi (2,625.03 km) |
| Southaven to Simpsonville (South Carolina) | 438.05 mi (704.97 km) |
| Southaven to Sioux City (Iowa) | 624.99 mi (1,005.83 km) |
| Southaven to Sioux Falls (South Dakota) | 694.16 mi (1,117.15 km) |
| Southaven to Skokie (Illinois) | 504.19 mi (811.42 km) |
| Southaven to Sleepy Hollow (New York) | 971.92 mi (1,564.15 km) |
| Southaven to Slidell (Louisiana) | 322.36 mi (518.79 km) |
| Southaven to Smithfield (North Carolina) | 657.07 mi (1,057.46 km) |
| Southaven to Smithfield (Utah) | 1,270.65 mi (2,044.91 km) |
