| Southaven to Santa Paula (California) | 1,647.88 mi (2,652.00 km) |
| Southaven to Santa Rosa (California) | 1,819.44 mi (2,928.11 km) |
| Southaven to Santaquin (Utah) | 1,242.09 mi (1,998.95 km) |
| Southaven to Santee (California) | 1,550.76 mi (2,495.71 km) |
| Southaven to Sapulpa (Oklahoma) | 352.03 mi (566.54 km) |
| Southaven to Saraland (Alabama) | 303.72 mi (488.79 km) |
| Southaven to Sarasota (Florida) | 685.07 mi (1,102.51 km) |
| Southaven to Sarasota Springs (Florida) | 689.30 mi (1,109.32 km) |
| Southaven to Saratoga (California) | 1,787.50 mi (2,876.70 km) |
| Southaven to Saratoga Springs (New York) | 1,032.11 mi (1,661.03 km) |
| Southaven to Saratoga Springs (Utah) | 1,252.80 mi (2,016.18 km) |
| Southaven to Sartell (Minnesota) | 769.91 mi (1,239.05 km) |
| Southaven to Satellite Beach (Florida) | 723.04 mi (1,163.62 km) |
| Southaven to Sauk Rapids (Minnesota) | 767.54 mi (1,235.24 km) |
| Southaven to Sault Ste. Marie (Michigan) | 848.47 mi (1,365.49 km) |
