| Southaven to Olympia (Washington) | 1,890.31 mi (3,042.16 km) |
| Southaven to Olympia Heights (Florida) | 857.47 mi (1,379.97 km) |
| Southaven to Omaha (Nebraska) | 546.68 mi (879.80 km) |
| Southaven to On Top of the World Designated Place (Florida) | 604.71 mi (973.18 km) |
| Southaven to Onalaska (Wisconsin) | 620.93 mi (999.29 km) |
| Southaven to Oneida (New York) | 949.59 mi (1,528.22 km) |
| Southaven to Oneonta (New York) | 954.55 mi (1,536.20 km) |
| Southaven to Ontario (California) | 1,569.52 mi (2,525.90 km) |
| Southaven to Ontario (Oregon) | 1,560.98 mi (2,512.15 km) |
| Southaven to Opa-locka (Florida) | 851.53 mi (1,370.41 km) |
| Southaven to Opelika (Alabama) | 307.90 mi (495.52 km) |
| Southaven to Opelousas (Louisiana) | 329.31 mi (529.98 km) |
| Southaven to Orange (California) | 1,584.62 mi (2,550.21 km) |
| Southaven to Orange (Texas) | 399.72 mi (643.29 km) |
| Southaven to Orange City (Florida) | 657.10 mi (1,057.50 km) |
