| Southaven to Enterprise (Nevada) | 1,418.53 mi (2,282.90 km) |
| Southaven to Enumclaw (Washington) | 1,851.98 mi (2,980.48 km) |
| Southaven to Ephrata (Pennsylvania) | 836.32 mi (1,345.92 km) |
| Southaven to Erie (Colorado) | 895.88 mi (1,441.79 km) |
| Southaven to Erie (Pennsylvania) | 728.25 mi (1,172.00 km) |
| Southaven to Erlanger (Kentucky) | 408.81 mi (657.91 km) |
| Southaven to Escanaba (Michigan) | 761.16 mi (1,224.96 km) |
| Southaven to Escondido (California) | 1,551.50 mi (2,496.90 km) |
| Southaven to Española (New Mexico) | 907.19 mi (1,459.99 km) |
| Southaven to Essex (Maryland) | 802.83 mi (1,292.03 km) |
| Southaven to Essex Junction (Vermont) | 1,108.85 mi (1,784.52 km) |
| Southaven to Estelle (Louisiana) | 352.91 mi (567.96 km) |
| Southaven to Estero (Florida) | 763.07 mi (1,228.04 km) |
| Southaven to Euclid (Ohio) | 648.21 mi (1,043.19 km) |
| Southaven to Eufaula (Alabama) | 348.72 mi (561.20 km) |
