| Southaven to Elyria (Ohio) | 615.87 mi (991.14 km) |
| Southaven to Emeryville (California) | 1,799.26 mi (2,895.63 km) |
| Southaven to Emmaus (Pennsylvania) | 878.73 mi (1,414.18 km) |
| Southaven to Emporia (Kansas) | 418.72 mi (673.86 km) |
| Southaven to Encinitas (California) | 1,563.43 mi (2,516.10 km) |
| Southaven to Endicott (New York) | 897.96 mi (1,445.13 km) |
| Southaven to Endwell (New York) | 900.53 mi (1,449.26 km) |
| Southaven to Englewood (Colorado) | 885.37 mi (1,424.86 km) |
| Southaven to Englewood (Florida) | 712.30 mi (1,146.34 km) |
| Southaven to Englewood (New Jersey) | 962.10 mi (1,548.35 km) |
| Southaven to Englewood (Ohio) | 460.35 mi (740.87 km) |
| Southaven to Enid (Oklahoma) | 454.02 mi (730.67 km) |
| Southaven to Ennis (Texas) | 423.57 mi (681.67 km) |
| Southaven to Ensley (Florida) | 343.78 mi (553.27 km) |
| Southaven to Enterprise (Alabama) | 346.12 mi (557.03 km) |
