| Southaven to Des Plaines (Illinois) | 502.08 mi (808.02 km) |
| Southaven to Desert Hot Springs (California) | 1,510.59 mi (2,431.05 km) |
| Southaven to DeSoto (Texas) | 427.37 mi (687.79 km) |
| Southaven to Destin (Florida) | 375.09 mi (603.65 km) |
| Southaven to Destrehan (Louisiana) | 345.44 mi (555.93 km) |
| Southaven to Detroit (Michigan) | 632.98 mi (1,018.68 km) |
| Southaven to Diamond Bar (California) | 1,581.83 mi (2,545.71 km) |
| Southaven to Diamond Springs (California) | 1,718.07 mi (2,764.97 km) |
| Southaven to Dickinson (North Dakota) | 1,059.28 mi (1,704.75 km) |
| Southaven to Dickinson (Texas) | 481.96 mi (775.64 km) |
| Southaven to Dickson (Tennessee) | 165.79 mi (266.82 km) |
| Southaven to Difficult Run (Virginia) | 748.35 mi (1,204.35 km) |
| Southaven to Dinuba (California) | 1,647.01 mi (2,650.60 km) |
| Southaven to Discovery Bay (California) | 1,761.19 mi (2,834.36 km) |
| Southaven to Dix Hills (New York) | 991.43 mi (1,595.55 km) |
