| South Lyon to St. Simons (Georgia) | 789.57 mi (1,270.70 km) |
| South Lyon to Stafford (Texas) | 1,106.30 mi (1,780.42 km) |
| South Lyon to Stallings (North Carolina) | 532.87 mi (857.58 km) |
| South Lyon to Stamford (Connecticut) | 528.12 mi (849.92 km) |
| South Lyon to Stanford (California) | 2,051.67 mi (3,301.84 km) |
| South Lyon to Stanton (California) | 1,944.77 mi (3,129.80 km) |
| South Lyon to Star (Idaho) | 1,648.55 mi (2,653.08 km) |
| South Lyon to Starkville (Mississippi) | 682.49 mi (1,098.36 km) |
| South Lyon to State College (Pennsylvania) | 320.74 mi (516.17 km) |
| South Lyon to Staten Island (New York) | 508.12 mi (817.73 km) |
| South Lyon to Statesboro (Georgia) | 700.15 mi (1,126.78 km) |
| South Lyon to Statesville (North Carolina) | 484.76 mi (780.15 km) |
| South Lyon to Staunton (Virginia) | 383.12 mi (616.56 km) |
| South Lyon to Steamboat Springs (Colorado) | 1,203.66 mi (1,937.11 km) |
| South Lyon to Steiner Ranch (Texas) | 1,148.22 mi (1,847.89 km) |
