| South Lyon to Siloam Springs (Arkansas) | 724.42 mi (1,165.83 km) |
| South Lyon to Silver Firs (Washington) | 1,891.76 mi (3,044.50 km) |
| South Lyon to Silver Spring (Maryland) | 421.30 mi (678.02 km) |
| South Lyon to Silver Springs Shores (Florida) | 926.82 mi (1,491.57 km) |
| South Lyon to Silverdale (Washington) | 1,917.30 mi (3,085.59 km) |
| South Lyon to Silverton (Oregon) | 1,942.30 mi (3,125.84 km) |
| South Lyon to Simi Valley (California) | 1,968.15 mi (3,167.42 km) |
| South Lyon to Simpsonville (South Carolina) | 539.54 mi (868.31 km) |
| South Lyon to Sioux City (Iowa) | 648.47 mi (1,043.62 km) |
| South Lyon to Sioux Falls (South Dakota) | 664.36 mi (1,069.18 km) |
| South Lyon to Skokie (Illinois) | 211.09 mi (339.71 km) |
| South Lyon to Sleepy Hollow (New York) | 512.42 mi (824.66 km) |
| South Lyon to Slidell (Louisiana) | 906.90 mi (1,459.52 km) |
| South Lyon to Smithfield (North Carolina) | 557.91 mi (897.86 km) |
| South Lyon to Smithfield (Utah) | 1,437.25 mi (2,313.04 km) |
