| South Lyon to Seymour (Indiana) | 269.58 mi (433.85 km) |
| South Lyon to Seymour (Tennessee) | 454.89 mi (732.07 km) |
| South Lyon to Shady Hills (Florida) | 973.23 mi (1,566.26 km) |
| South Lyon to Shafter (California) | 1,954.17 mi (3,144.94 km) |
| South Lyon to Shaker Heights (Ohio) | 127.75 mi (205.60 km) |
| South Lyon to Shakopee (Minnesota) | 516.37 mi (831.03 km) |
| South Lyon to Sharon (Pennsylvania) | 183.08 mi (294.64 km) |
| South Lyon to Sharonville (Ohio) | 223.15 mi (359.12 km) |
| South Lyon to Shasta Lake (California) | 1,988.13 mi (3,199.59 km) |
| South Lyon to Shawnee (Kansas) | 630.02 mi (1,013.91 km) |
| South Lyon to Shawnee (Oklahoma) | 866.39 mi (1,394.33 km) |
| South Lyon to Sheboygan (Wisconsin) | 223.92 mi (360.36 km) |
| South Lyon to Shelby (North Carolina) | 508.22 mi (817.90 km) |
| South Lyon to Shelbyville (Indiana) | 230.58 mi (371.08 km) |
| South Lyon to Shelbyville (Kentucky) | 305.46 mi (491.59 km) |
